This paper proposed a new location method for the single-phase grounding fault of power cable based on time-reversal technology. When the single-phase grounding fault of power cable occurred, this method used the time-reversal symmetry of voltage wave equation, inverted the time-domain voltage wave collected at the line terminals into an equivalent current wave and returned it to the transmission line; then calculated the energy value of the current through the assumed fault point, determined the distance of fault point to the line terminal based on the time-space synchronization focusing properties. Matlab simulation results show that the method can accurately and effectively achieve the single-phase grounding fault location of power cable, and not only be applicable to the ground faults with different fault resistances, also have the characteristics of fast convergence speed and high fault location precision.