The main purpose of demand side resources participating in power grid interaction is to achieve both ends of the ‘source-network-load’ regulation, and ensure the real-time balance of power grid. Block chain technology is a kind of network accounting approach based on the distributed system, and the information architecture with high redundancy can realize the reproduction of safety information. In order to ensure the security and reliability of information, this paper designs the system architecture for the interaction between supply and demand based on the block chain with considering the interactive mode in the smart grid concept model, and proposes a design idea of integrated information platform, which takes a block chain protocol standard as support, information monitoring, collection, input, statistics as the center, demand response automation server (DRAS), load integrator and user group as framework. The results show that the architecture system based on block chain can make the information cannot be tampered, and the security of the whole system is not limited to a central point of failure, which can ensure the security and reliability of information.